PLE-2741

An 82-year-old woman is brought to the emergency department 30 minutes after collapsing at a shopping center. She was intubated at the scene. On admission, she is comatose and requires mechanical ventilation. Her pulse is 120/min, respirations are 12/min, and blood pressure is 90/60 mm Hg. She does not respond to painful stimuli. Thirty minutes later, her granddaughter comes to the hospital and shows the physician an advance directive signed by the patient requesting no intubation or artificial means to prolong life. Which of the following is the most appropriate next step in management?