PLE-6268

A 37-year-old man comes to the physician because of a 1-week history of pain with swallowing. He received the diagnosis of AIDS 4 years ago but has not been able to tolerate highly active antiretroviral therapy. He currently takes TMP-SMX. Vital signs are within normal limits. Examination shows a few white plaques over the pharynx. CD4+ count is 50/mm3, and plasma HIV viral load is 50,000 copies/mL. Which of the following is the most appropriate pharmacotherapy?