PLE-6269

PLE-6269

A 47-year-old woman comes to the physician for a routine health maintenance examination. She has a 2-year history of venous insufficiency and noted daily swelling of her ankles that worsens in the evening. She takes no medications. Her pulse is 80 bpm, and blood pressure is 160/100 mmHg. Cardiopulmonary examination shows no abnormalities. Examination of the lower extremities shows 2+ edema and increased pigmentation. Which of the following antihypertensive medications would most likely exacerbate this patient’s swelling?