PLE Category: Internal Medicine

PLE-2037

A 25-year-old male, known case of Hemophilia A with a history of multiple Factor VIII concentrate transfusions, was admitted due to bilateral knee swelling. Despite transfusion with adequate levels of Factor VIII concentrate, levels of the said factor remain decreased. Which of the following statements regarding the patient’s current predicament is true?

PLE-2038

What is the target blood pressure in chronic kidney disease (CKD) patients with diabetes or proteinuria of > 1g/24hr?

PLE-2039

A 23-year-old male sought consultation due to polyuria. Physical examination was essentially normal. Blood tests showed normal fasting blood sugar (FBS) and HbA1C levels. Plasma osmolality and serum sodium levels were both elevated. Urinalysis was performed, which showed a decreased specific gravity. A water deprivation test was conducted, but it did not result in urine concentration. Vasopressin was administered, but it also failed to concentrate the urine. What is the most likely diagnosis for this case?

PLE-2035

To what location does the murmur of mitral regurgitation most commonly radiate?

PLE-2036

A 29-year-old female presented with weight loss, palpitation, tremors, and heat intolerance. She is tachycardic at 115 bpm with the presence of moderate to severe proptosis. The thyroid gland is diffusely enlarged and non-tender. Reflexes are hyperactive. The rest of the examination is normal. Which of the following treatment options may worsen her proptosis?

PLE-2032

A 58-year-old male was brought to the ER due to a one-week history of progressive headache and fever. He has been diagnosed with Pulmonary Tuberculosis but has been unable to start his medications due to financial difficulties. On examination, he was drowsy but arousable with note of nuchal rigidity and a positive Brudzinski sign. Lumbar puncture was done, which showed an elevated WBC count of lymphocytic predominance, an elevated protein level, and a decreased glucose level. Which of the following statements is true regarding the most probable condition of the patient?

PLE-2033

Which joint is spared in osteoarthritis?

PLE-2034

A 40-year-old female was referred for hematologic evaluation because of findings of splenomegaly and a markedly elevated WBC count of 180,000/uL with the following differential count: Blasts 2%, Promyelocyte 15%, Metamyelocyte 20%, Myelocyte 10%, Bands 8%, Segmenters 30%, Lymphocytes 10%, and Basophils 5%. The hematologist made a primary diagnosis of CML. Which of the following treatment options for this case induces rapid disease control by lowering the WBC count?

PLE-2030

In the recovery phase of acute renal failure, which of the following possible complications should one be most concerned about?