A pale 7-year-old girl from a poor rural area of Appalachia presents with chronic complaints of tiredness, upset tummy and the runs She is found to have microcytic hypochromic anemia. Bile-stained eggs with polar plugs are found in her feces. This infection can be prevented by
A patient has a dry, scaly, erythematous penis. Skin scales stained with calcofluor white show fluorescent blue-white yeasts and a few pseudohyphae. What is the causative agent of this dermatophytic look-alike?
A newborn with extremely low Apgar scores passes away 3 hours after delivery. Post-mortem examination reveals widespread granulomatous lesions throughout the body, some of which are caseating but not calcified. It is suspected that the mother had a septicemia during her pregnancy caused by:
A non-vaccinated 6-year-old British child just returning from Africa presents with a severe sore throat but little fever. The throat has a grayish exudate on the sides of the pharynx and the child has a swollen neck. Clinical suspicion is of a disease with a circulating toxin inhibiting protein synthesis. What additional tissues are frequently involved?
A noncompliant 71-year-old HIV-positive man with a CD4 cell count of 40/mm3 presents with a pulmonary infection caused by an organism that requires 4 weeks to grow on Lowenstein-Jensen medium. What is the best descriptor of the most likely causative agent?
A neonate develops meningitis at 8 days of age. Her mother is 17 years of age, single, has had multiple sexual partners without barrier protection, and lives in the United States. The baby was born 23 hours after the mother’s amniotic sac ruptured. What is the most likely causative agent?
A new infectious agent has been isolated from mosquitoes. It lacks a cell wall but has 70S ribosomes. This agent is most likely a
A new reverse transcriptase has been discovered. In addition to its effect on HIV disease, it should be checked for its potential in treating other patients.
A newborn is suspected to have combined immunodeficiency disease (SCID). (One previous sibling died of this.) Which of the following would confirm the diagnosis?
A middle-aged woman presents with chronic fatigue, difficulty sleeping, a rapid heartbeat, and bulging eyes. Lab tests revealed autoantibodies to thyroid-stimulating hormone. The most likely diagnosis is