A 23-year-old female student complains of excessive fatigue for the past 2 months. Polyarthralgia and vasculitis is noted on examination. Lab tests reveal multiple autoantibodies including antidouble-stranded DNA. The most logical diagnosis is
A 23-year-old man with cystic fibrosis presents with fever and increasing dyspnea. A Gram-negative organism is found in unusually high numbers in the pulmonary mucus. Which virulence factor is most important in colonization and maintenance of the organism in the lungs?
A 22-year-old male college student who had complained of headache and feeling feverish the night before is brought this morning to the emergency department (ED) when his roommate was unable to rouse him. He had been well until yesterday. Vital signs include fever (39.8°C/103.1°F), tachycardia, and hypotension (BP 70/55). Remarkable on physical examination is petechial rash (purpuric in areas) and nuchal rigidity with positive Kernig and Brudzinski signs. CSF is cloudy with high protein and low glucose. Intracellular, red diplococci are seen on Gram stain. What is the most likely genus?
A 19-year-old New York dirt bike racer, who recently raced for the first time in races along the Mississippi and also in the desert southwest, presents in September with cough, malaise, low-grade fever, myalgias, and chest pain. Rales are heard and respiratory infiltrates are noted on radiograph. Sputum stained with calcofluor white and viewed with an ultraviolet microscope shows hundreds of tiny yeast cells inside white cells. If cultured at room temperature, hyphae with small microconidia and tuberculate macroconidia would grow. What is the most likely causative agent?
A 20-year-old college freshman has a sore throat, sore and enlarged cervical lymph nodes, and a fever. The student is also greatly fatigued. A diagnosis of infectious mononucleosis is made. Which of the following factors is present?
A 20-year-old pregnant student presents at her health service allergy clinic with rhinorrhea, sneezing, itching, and conjunctivitis. A RAST test finds IgE antibodies to ragweed antigens. A characteristic of this condition is
A 16-year-old dirt-bike rider visiting southern California for the first time has developed pneumonia. The causative organism has an environmental form that consists of hyphae that break up into arthroconidia, which become airborne. What is the agent?
A 16-year-old girl presents to your gynecology clinic with complaints of recurring pelvic pain. A probable diagnosis of pelvic inflammatory disease is made. She is a junior at a suburban high school, is involved in orchestra, and has been on the honor roll most years. She does not do drugs. She has had an equally squeaky clean type of boyfriend since last fall, and 6 months ago they had unprotected sex on three occasions. What is the most likely causative agent?
A 16-year-old male visiting his grandparents in Louisiana in August develops a severe unrelenting headache that is not relieved by analgesics. He is very sleepy and complains about an odd odor that he thinks is in the whole house. Primary amebic meningoencephalitis is diagnosed. How was it most likely acquired?
A 17-month-old female infant is brought to the emergency department by her mother. The mother reports an abrupt onset of symptoms consisting of continual crying, high fever (40°C/104°F), and a cough producing rusty colored sputum. What would you expect a chest x-ray and lab findings to show?