PLE Category: Pharmacology

PLE-6299

Which novel and innovative drug is used to treat rheumatoid arthritis through its action as an antibody against the protein CD20, found on the surface of B cells?

PLE-6289

Local anesthetics block nerve conduction through inhibition of which electrolyte?

PLE-6290

What is the incidence of Reye syndrome among patients less than 20 who took Aspirin concurrent with influenza A/B infection?

PLE-6291

What is a fusion inhibitor used in the treatment of HIV infection?

PLE-6292

In dermatologic pharmacology, approximately how many grams of topical preparation are needed to cover the body surface?

PLE-6285

Sisa, a 28-year-old female who was recently diagnosed with schizophrenia, was admitted to the Psychiatry ward and started on Risperidone. Three days later, the patient developed a fever (39.9°C) and rigidity. The patient was notably confused. The vital signs were as follows: BP 170/120, HR 118, RR 22. What could explain Sisa’s symptoms?

PLE-6286

Why is acyclovir an effective antiviral for a 10-year-old female diagnosed with HSV encephalitis when given intravenously?

PLE-6287

A 55-year-old male comes in due to a sudden headache described as the worst headache of his life. He is diagnosed with hypertension but has poor compliance with medications. Physical examination reveals nuchal tenderness (positive Kernig’s sign) and a left cranial nerve palsy. Brain CT reveals diffuse subarachnoid hemorrhage in the basal cisterns. Which of the following drugs has a proven role in the management of his condition?

PLE-6288

Can you provide a second generation Cephalosporin that has intrinsic activity against anaerobes?