PLE-1318
What is the result of a deficiency in this enzyme? It causes intracellular accumulation of sorbitol, leading to osmotic damage in the form of cataracts, retinopathy, and peripheral neuropathy seen in uncontrolled diabetics.
What is the result of a deficiency in this enzyme? It causes intracellular accumulation of sorbitol, leading to osmotic damage in the form of cataracts, retinopathy, and peripheral neuropathy seen in uncontrolled diabetics.