PLE-5759

A 23-year-old female, who is a previous RHD patient s/p valve replacement and is currently on warfarin, presented at the ER. Three days prior, she experienced symptoms of PUD and self-medicated. She now has black tarry stools, epigastric pain, coffee ground emesis, gum bleeding, and dizziness. Laboratory results showed a prolonged PT. Which of the following drugs caused a drug interaction with warfarin, prolonging its anticoagulant effect?